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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EVI5
All Species:
22.12
Human Site:
Y274
Identified Species:
69.52
UniProt:
O60447
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60447
NP_005656.4
810
92935
Y274
F
V
K
L
M
Q
D
Y
R
L
R
E
L
F
K
Chimpanzee
Pan troglodytes
XP_513563
810
93027
Y274
F
V
K
L
M
Q
D
Y
R
L
R
E
L
F
K
Rhesus Macaque
Macaca mulatta
XP_001099693
810
92963
Y274
F
V
K
L
M
Q
D
Y
R
L
R
E
L
F
K
Dog
Lupus familis
XP_537075
825
95145
Y230
F
V
K
L
M
Q
D
Y
R
L
R
E
L
F
K
Cat
Felis silvestris
Mouse
Mus musculus
P97366
809
92924
Y274
F
V
K
L
M
Q
D
Y
R
L
R
E
L
F
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512280
425
49637
V23
D
S
K
S
L
R
S
V
N
G
S
R
R
N
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY9
807
92764
R229
I
M
Q
Q
H
R
M
R
H
M
F
K
P
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799050
880
100294
Y350
L
V
K
I
M
Q
E
Y
G
M
R
E
L
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
89.9
N.A.
89.6
N.A.
N.A.
48.7
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
N.A.
45.5
Protein Similarity:
100
99.7
99.5
91.1
N.A.
94.1
N.A.
N.A.
50.8
N.A.
N.A.
N.A.
N.A.
57
N.A.
N.A.
63.9
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
63
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
13
0
0
0
0
75
0
0
0
% E
% Phe:
63
0
0
0
0
0
0
0
0
0
13
0
0
75
0
% F
% Gly:
0
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% G
% His:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
88
0
0
0
0
0
0
0
0
13
0
0
75
% K
% Leu:
13
0
0
63
13
0
0
0
0
63
0
0
75
0
0
% L
% Met:
0
13
0
0
75
0
13
0
0
25
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% P
% Gln:
0
0
13
13
0
75
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
25
0
13
63
0
75
13
13
0
0
% R
% Ser:
0
13
0
13
0
0
13
0
0
0
13
0
0
13
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
75
0
0
0
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _